CRISPR can now be run on many sequences at once, for rapid discovery of gRNA candidates across many targets.
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More Options for Gibson Assembly and CRISPR (R9.1) Full support for the full array of scarless methods including SLIC, SLiCE, CPEC, InFusion and GeneArt Seamless. Greater Control for Alignments (R9.1) Redesigned go to next controls give more power in a more intuitive interface. Options to control how many mismatches and indels are allowed when scoring against off-targets.
Cutting edge CRISPR New scoring strategy for on-target activity. Greatly improved performance when loading and rendering trees. Big Trees New search box for finding nodes and taxa, and automatic collapsing of sub-trees based on distances. For DNA sequencing, you can now discover structural variants and annotate them, allowing for correct alignments of read-ends around deletions and structural rearrangements in heterozygous samples. RNA- Seq and Structural Variant Mapping Map RNA-seq using existing annotated coding regions or discover novel intron and fusion genes during mapping. Golden Gate Intelligent handling of preconfigured Golden Gate parts and automatic designing of primers for new parts. Sequence and alignment view is now scaled according to your display.
Sequences in the multiple alignment are now highlighted according to coloring in the tree. Updated to new modern font for high quality publications, cleaner plasmid maps and retina screens. Geneious is used by all 20 of the top 20 Universities globally (Times Higher Education, 2012) and by seven of the 10 largest pharmaceutical companies.Ĭleaner, Clearer and Scalable Displays (R9.1) Better support for HiDPI displays on Windows and Linux.
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